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New England Biolabs (NEB) produces and supplies recombinant and native enzyme reagents for the life science research.〔Philippides 2013〕 NEB also provides free access to research tools such as REBASE, InBASE, and Polbase. ==The company== Established in 1974 by Donald Comb, as a cooperative laboratory of experienced scientists, and initially produced restriction enzymes on a commercial scale. The company then began producing solution-oriented products. It received approximately $1.7 million in Small Business Innovation Research (SBIR) grants between 2009 and 2013 for this research.〔 NEB produces 230 recombinant and 30 native restriction enzymes for genomic research, as well as nicking enzymes and DNA methylases. It pursues research in areas related to proteomics, DNA Sequencing, and drug discovery. NEB scientists also conduct basic research in Molecular Biology and Parasitology. The company has subsidiaries in Singapore, Canada, China, France, Germany, Japan, and the U.K.〔 and distributors in South America, Australia, and other countries in Europe and Asia.〔(【引用サイトリンク】publisher=Business Week )〕 Its headquarters are in Ipswich, MA. Development of the current headquarters began in 2000, and was completed in 2005. Donald Comb served as the company’s Chairman and CEO from the company’s founding in 1974, until 2005. In 2005, he was replaced as chief executive by James Ellard, though Comb remained Chairman. Richard Roberts is the company’s Chief Scientific Officer. NEB employs about 350 people at its headquarters. As company policy, all scientists and some executives must work at least one day per month on the customer support telephone line, answering technical support questions about the company’s products. In 2015, NEB committed to establishing a GMP manufacturing facility near its headquarters in Ipswich, Massachusetts; the aim is to be fully validated and operational by 2017. ==Databases== The company runs free scientific databases. REBASE, the restriction enzyme database, contains the details of commercial and research endonucleases. In 2011 the company founded Polbase, an online database which provides information specifically about polymerases.〔(【引用サイトリンク】publisher=Genome Web )〕 Another free NEB database is InBase, an intein database, which includes the Intein Registry and information about each intein. 抄文引用元・出典: フリー百科事典『 ウィキペディア（Wikipedia）』 ■ウィキペディアで「New England Biolabs」の詳細全文を読む スポンサード リンク
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